Born on 22nd Feb 1978 to Mr. And Mr. De-Mensah, Henry De-Mensah as he was named began his primary education continued at Preseco Nungua. His talent, which was discovered in his early teens, developed through dancing, rapping and finally the aggressive young singer Nana Quame was born. Nana Quame at a very tender age started-performing in talent show despite his extremely young age he won a talent show on national television doing the rendition of the Ghanaian musician Kojo Antwi.